Critical Unauthenticated RCE Vulnerabilities in Cisco ISE and ISE-PIC 

Cisco has disclosed two critical vulnerabilities CVE-2025-20281 and CVE-2025-20282 affecting its Identity Services Engine (ISE) and Passive Identity Connector (ISE-PIC).

These vulnerabilities allow unauthenticated, remote attackers to execute arbitrary commands on the underlying operating system with root privileges. The first flaw CVE-2025-20281 impacts ISE versions 3.3 and later, while the second CVE-2025-20282 is limited to version 3.4.

Summary 

OEM Cisco 
Severity Critical 
CVSS Score 10.0 
CVEs CVE-2025-20281, CVE-2025-20282 
POC Available No 
Actively Exploited No 
Exploited in Wild No 
Advisory Version 1.0 

Overview 

Cisco has disclosed two critical vulnerabilities CVE-2025-20281 and CVE-2025-20282 affecting its Identity Services Engine (ISE) and Passive Identity Connector (ISE-PIC).

These vulnerabilities allow unauthenticated, remote attackers to execute arbitrary commands on the underlying operating system with root privileges. The first flaw CVE-2025-20281 impacts ISE versions 3.3 and later, while the second CVE-2025-20282 is limited to version 3.4.

Both issues stem from insecure API implementations that fail to validate user input and uploaded files respectively.  

Given the critical nature of these bugs both scoring CVSS 9.8 & 10.0 Cisco has issued immediate fixes, with no workarounds available. Organizations using the affected versions are urged to apply the patches without delay. 

Vulnerability Name CVE ID Product Affected Severity Fixed Version 
​API Unauthenticated RCE vulnerability  CVE-2025-20281 ISE & ISE-PIC   Critical  3.3 Patch 6, 3.4 Patch 2 
Internal API Arbitrary File Execution vulnerability  CVE-2025-20282 ISE & ISE-PIC   Critical  3.4 Patch 2 

Technical Summary 

Two independent vulnerabilities allow an attacker to gain full control over affected Cisco ISE systems without authentication: 

  • CVE-2025-20281: Triggered via crafted requests to a public API, exploiting insufficient input validation to achieve RCE as root. 
  • CVE-2025-20282: Abuses an internal API that lacks file validation, enabling the upload and execution of malicious files in privileged directories. 

These vulnerabilities align with CWE-74 (Improper Neutralization of Special Elements in Output Used by a Downstream Component) and CWE-269 (Improper Privilege Management). 

CVE ID System Affected  Vulnerability Details Impact 
CVE-2025-20281 Cisco ISE & ISE-PIC 3.3 and later Insufficient validation in a public API allows remote attackers to send crafted requests, leading to unauthenticated command execution as the root user.  Remote code execution  
CVE-2025-20282 Cisco ISE & ISE-PIC 3.4 only An internal API fails to validate uploaded files. Attackers can upload files to system directories and execute them with root privileges.   Remote code execution 

Remediation

Cisco has released patches for affected versions of ISE and ISE-PIC. There are no known workarounds, and customers are strongly encouraged to apply the following updates: 

Cisco ISE / ISE-PIC Version CVE-2025-20281 Fixed In CVE-2025-20282 Fixed In 
3.2 and earlier Not affected Not affected 
3.3 3.3 Patch 6 Not affected 
3.4 3.4 Patch 2 3.4 Patch 2 

Conclusion: 
These vulnerabilities represent a severe risk to network security infrastructure, particularly because they impact Cisco ISE a cornerstone for identity and access control in many enterprises. The unauthenticated remote nature of the exploits, combined with root-level access and no required user interaction, significantly increases the threat surface.  

Although Cisco’s PSIRT has stated that there are no known instances of public exploitation, the ease of exploitation and severity (CVSS 10.0) make these vulnerabilities highly attractive to threat actors. Organizations should immediately apply the available patches and review their system logs for any signs of suspicious activity targeting ISE infrastructure. 

References

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